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Hypothalamic melanocortin signaling and leptin resistance―Perspective of therapeutic application for obesity-diabetes syndromeMASUZAKI, Hiroaki; TANAKA, Tomohiro; EBIHARA, Ken et al.Peptides (New York, NY. 1980). 2009, Vol 30, Num 7, pp 1383-1386, issn 0196-9781, 4 p.Article

Translational research of novel hormones: lessons from animal models and rare human diseases for common human diseasesNAKAO, Kazuwa; YASODA, Akihiro; EBIHARA, Ken et al.Journal of molecular medicine (Berlin. Print). 2009, Vol 87, Num 10, pp 1029-1039, issn 0946-2716, 11 p.Article

Impaired CNS Leptin Action Is Implicated in Depression Associated with ObesityYAMADA, Nobuko; KATSUURA, Goro; OCHI, Yukari et al.Endocrinology (Philadelphia). 2011, Vol 152, Num 7, pp 2634-2643, issn 0013-7227, 10 p.Article

Effects of ghrelin administration on decreased growth hormone status in obese animalsIWAKURA, Hiroshi; AKAMIZU, Takashi; ARIYASU, Hiroyuki et al.American journal of physiology. Endocrinology and metabolism. 2007, Vol 56, Num 3, issn 0193-1849, E819-E825Article

Establishment of a novel neuroblastoma mouse modelIWAKURA, Hiroshi; ARIYASU, Hiroyuki; KANAMOTO, Naotetsu et al.International journal of oncology. 2008, Vol 33, Num 6, pp 1195-1199, issn 1019-6439, 5 p.Article

Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivoBANDO, Mika; IWAKURA, Hiroshi; ARIYASU, Hiroyuki et al.American journal of physiology. Endocrinology and metabolism. 2012, Vol 65, Num 2, issn 0193-1849, E403-E408Article

Adipose Tissue-Specific Regulation of Angiotensinogen in Obese Humans and Mice: Impact of Nutritional Status and Adipocyte HypertrophyYASUE, Shintaro; MASUZAKI, Hiroaki; OHASHI, Naro et al.American journal of hypertension. 2010, Vol 23, Num 4, pp 425-431, issn 0895-7061, 7 p.Article

Troglitazone not only increases GLUT4 but also induces its translocation in rat adipocytesSHINTANI, Mitsuyo; NISHIMURA, Haruo; YONEMITSU, Shin et al.Diabetes (New York, NY). 2001, Vol 50, Num 10, pp 2296-2300, issn 0012-1797Article

Intracerebroventricular Administration of C-Type Natriuretic Peptide Suppresses Food Intake via Activation of the Melanocortin System in MiceYAMADA-GOTO, Nobuko; KATSUURA, Goro; HOSODA, Kiminori et al.Diabetes (New York, NY). 2013, Vol 62, Num 5, pp 1500-1504, issn 0012-1797, 5 p.Article

Possible involvement of the α1 isoform of 5'AMP-activated protein kinase in oxidative stress-stimulated glucose transport in skeletal muscleTOYODA, Taro; HAYASHI, Tatsuya; OTAKA, Akira et al.American journal of physiology. Endocrinology and metabolism. 2004, Vol 50, Num 1, pp E166-E173, issn 0193-1849Article

Thiazolidinediones, peroxisome proliferator-activated receptor γ agonists, regulate endothelial cell growth and secretion of vasoactive peptidesFUKUNAGA, Yasutomo; ITOH, Hiroshi; HOSODA, Kiminori et al.Atherosclerosis. 2001, Vol 158, Num 1, pp 113-119, issn 0021-9150Article

Troglitazone induces GLUT4 translocation in L6 myotubesYONEMITSU, Shin; NISHIMURA, Haruo; NAKAO, Kazuwa et al.Diabetes (New York, NY). 2001, Vol 50, Num 5, pp 1093-1101, issn 0012-1797Article

Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humansARIYASU, Hiroyuki; TAKAYA, Kazuhiko; SHIRAKAMI, Gotaro et al.The Journal of clinical endocrinology and metabolism. 2001, Vol 86, Num 10, pp 4753-4758, issn 0021-972XArticle

Ghrelin strongly stimulates growth hormone (GH) release in humansTAKAYA, Kazuhiko; ARIYASU, Hiroyuki; OGAWA, Yoshihiro et al.The Journal of clinical endocrinology and metabolism. 2000, Vol 85, Num 12, pp 4908-4911, issn 0021-972XArticle

Oxytocin and Dopamine Stimulate Ghrelin Secretion by the Ghrelin-Producing Cell Line, MGN3-1 in VitroIWAKURA, Hiroshi; ARIYASU, Hiroyuki; HOSODA, Hiroshi et al.Endocrinology (Philadelphia). 2011, Vol 152, Num 7, pp 2619-2625, issn 0013-7227, 7 p.Article

Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic MiceNAITO, Masaki; FUJIKURA, Junji; NAKAO, Kazuwa et al.Diabetes (New York, NY). 2011, Vol 60, Num 9, pp 2265-2273, issn 0012-1797, 9 p.Article

Effect of acute activation of 5'-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscleMIYAMOTO, Licht; TOYODA, Taro; INOUE, Gen et al.Journal of applied physiology (1985). 2007, Vol 102, Num 3, pp 1007-1013, issn 8750-7587, 7 p.Article

Transgenic expression of mutant peroxisome proliferator-activated receptor y in liver precipitates fasting-induced steatosis but protects against high-fat diet-induced steatosis in miceTANAKA, Tomohiro; MASUZAKI, Hiroaki; KUSAKABE, Toru et al.Metabolism, clinical and experimental. 2005, Vol 54, Num 11, pp 1490-1498, issn 0026-0495, 9 p.Article

Gene and phenotype analysis of congenital generalized lipodystrophy in Japanese: A novel homozygous nonsense mutation in seipin geneEBIHARA, Ken; KUSAKABE, Toru; OGAWA, Yoshihiro et al.The Journal of clinical endocrinology and metabolism. 2004, Vol 89, Num 5, pp 2360-2364, issn 0021-972X, 5 p.Article

Altered gene expression of uncoupling protein-2 and -3 in stroke-prone spontaneously hypertensive ratsFUKUNAGA, Yasutomo; ITOH, Hiroshi; MASATSUGU, Ken et al.Journal of hypertension. 2000, Vol 18, Num 9, pp 1233-1238, issn 0263-6352Article

High-fat diet impairs the effects of a single bout of endurance exercise on glucose transport and insulin sensitivity in rat skeletal muscleTANAKA, Satsuki; HAYASHI, Tatsuya; NAKAO, Kazuwa et al.Metabolism, clinical and experimental. 2007, Vol 56, Num 12, pp 1719-1728, issn 0026-0495, 10 p.Article

Association of Ob-R gene polymorphism and insulin resistance in Japanese menTAKAHASHI-YASUNO, Akiko; MASUZAKI, Hiroaki; MIYAWAKI, Takashi et al.Metabolism, clinical and experimental. 2004, Vol 53, Num 5, pp 650-654, issn 0026-0495, 5 p.Article

Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese menTAKAHASHI-YASUNO, Akiko; MASUZAKI, Hiroaki; MIYAWAKI, Takashi et al.Diabetes research and clinical practice. 2003, Vol 62, Num 3, pp 169-175, issn 0168-8227, 7 p.Article

C-Type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelializationDOI, Kentaro; IKEDA, Tadashi; SAWADA, Naoki et al.Arteriosclerosis, thrombosis, and vascular biology. 2001, Vol 21, Num 6, pp 930-936, issn 1079-5642Article

Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathwaySHINTANI, Mitsuyo; OGAWA, Yoshihiro; KANGAWA, Kenji et al.Diabetes (New York, NY). 2001, Vol 50, Num 2, pp 227-232, issn 0012-1797Article

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